使用Interaction.Triggers可以對依賴屬性進行命令響應，適合在Prism框架中使用ViewModel進行命令繫結。

使用Interaction需要引用System.Windows.Interactivity。

參考：WPF how to bind mousedown (command/action) to label

1、View

<Grid>
    <Border Style="{StaticResource BorderRegion}">
        <Grid>
            <i:Interaction.Triggers>
                <i:EventTrigger EventName="
 
PreviewMouseDown">
                    <i:InvokeCommandAction Command="{Binding SelectGridCommand}"/>
                </i:EventTrigger>
            </i:Interaction.Triggers>
        </Grid>
    </Border>
</Grid>

2、ViewModel

public class WindowViewModel : BindableBase
{
    
 
public DelegateCommand SelectGridCommand { get; }

    public WindowViewModel()
    {
        SelectGridCommand = new DelegateCommand(SelectGrid, CanExecute);
    }
    
    private static bool CanExecute()
    {
        return true;
    }

    private void SelectGrid()
    {
    }
}