1.使用中科大源
（1）替換預設源 
第一步：替換brew.git

cd "$(brew --repo)"
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git remote set-url origin https://mirrors.ustc.edu.cn/brew.git
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第二步：替換homebrew-core.git

cd "$(brew --repo)/Library/Taps/homebrew/homebrew-core"
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git remote set-url origin https://mirrors.ustc.edu.cn/homebrew-core.git
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cd 
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2
brew update
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（2）替換Homebrew Bottles源

Homebrew是OS X系統的一款開源的包管理器。出於節省時間的考慮，Homebrew預設從Homebrew Bottles源中下載二進位制程式碼包安裝。Homebrew Bottles是Homebrew提供的二進位制程式碼包，目前映象站收錄了以下倉庫： 
homebrew/homebrew-core 
homebrew/homebrew-dupes 
homebrew/homebrew-games 
homebrew/homebrew-gui 
homebrew/homebrew-python 
homebrew/homebrew-php 
homebrew/homebrew-science 
homebrew/homebrew-versions 
homebrew/homebrew-x11

對於bash使用者：

echo 'export HOMEBREW_BOTTLE_DOMAIN=https://mirrors.ustc.edu.cn/homebrew-bottles' >> ~/.bash_profile
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source ~/.bash_profile
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對於zsh使用者

echo 'export HOMEBREW_BOTTLE_DOMAIN=https://mirrors.ustc.edu.cn/homebrew-bottles' >> ~/.zshrc
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source ~/.zshrc
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2.使用清華源
（1）替換預設源 
第一步：替換現有上游

cd "$(brew --repo)"
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git remote set-url origin https://mirrors.tuna.tsinghua.edu.cn/git/homebrew/brew.git
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cd "$(brew --repo)/Library/Taps/homebrew/homebrew-core"
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git remote set-url origin https://mirrors.tuna.tsinghua.edu.cn/git/homebrew/homebrew-core.git
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cd 
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2
drew update
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第二步：使用homebrew-science或者homebrew-python

cd "$(brew --repo)/Library/Taps/homebrew/homebrew-science"
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git remote set-url origin https://mirrors.tuna.tsinghua.edu.cn/git/homebrew/homebrew-science.git
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或

cd "$(brew --repo)/Library/Taps/homebrew/homebrew-python"
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git remote set-url origin https://mirrors.tuna.tsinghua.edu.cn/git/homebrew/homebrew-python.git
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cd 
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2
brew update
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（2）替換Homebrew Bottles源

echo 'export HOMEBREW_BOTTLE_DOMAIN=https://mirrors.tuna.tsinghua.edu.cn/homebrew-bottles' >> ~/.bash_profile
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source ~/.bash_profile
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3.在中科大源或清華源失效或宕機時可以切換回官方源
第一步：重置brew.git

cd "$(brew --repo)"
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git remote set-url origin https://github.com/Homebrew/brew.git
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第二步：重置homebrew-core.git

cd "$(brew --repo)/Library/Taps/homebrew/homebrew-core"
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git remote set-url origin https://github.com/Homebrew/homebrew-core.git
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cd
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brew update
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第三步：註釋掉bash配置檔案裡的有關Homebrew Bottles即可恢復官方源。 重啟bash或讓bash重讀配置檔案。
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原文：https://blog.csdn.net/lwplwf/article/details/79097565?utm_source=copy 
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