A framework /Library/Frameworks/Python.framework, which includes the Python executable and libraries. 
The installer adds this location to your shell path. 
To uninstall MacPython, you can simply remove these three things. 
A symlink to the Python executable is placed in /usr/local/bin/.

The Apple-provided build of Python is installed in /System/Library/Frameworks/Python.framework and /usr/bin/python, respectively.
You should never modify or delete these, as they are Apple-controlled and are used by Apple- or third-party software. 
Remember that if you choose to install a newer Python version from python.org, 
you will have two different but functional Python installations on your computer, 
so it will be important that your paths and usages are consistent with what you want to do.
 

簡單來說就是

• 刪除 /Library/Frameworks/Python.framework

• 刪除 /usr/local/bin/ 下的 python 連結(symlink)

注意：蘋果系統需要python的支援，無論如何不要修改刪除這兩個資料夾

/System/Library/Frameworks/Python.framework and /usr/bin/python.

最後還需要刪除Application下的python資料夾