目前可以隨即選取4個網站中一張美女圖片，來作為桌布。

import random
import requests
from lxml import etree
from fake_useragent import UserAgent
import win32api
import win32gui
import win32con
import os
import re
import urllib

def set_wallpaper(bmp_path):
    # 開啟指定登錄檔路徑
    reg_key = win32api.RegOpenKeyEx(win32con.HKEY_CURRENT_USER, "
 
Control Panel\\Desktop", 0, win32con.KEY_SET_VALUE)
    # 最後的引數:2拉伸,0居中,6適應,10填充,0平鋪
    win32api.RegSetValueEx(reg_key, "WallpaperStyle", 0, win32con.REG_SZ, "2")
    # 最後的引數:1表示平鋪,拉伸居中等都是0
    win32api.RegSetValueEx(reg_key, "TileWallpaper", 0, win32con.REG_SZ, "0")
    # 重新整理桌面
    win32gui.SystemParametersInfo(win32con.SPI_SETDESKWALLPAPER,bmp_path, win32con.SPIF_SENDWININICHANGE)
 
class bizhi_360():
    def __init__(self):
        bizhi_360 = ['http://bizhi360.com/meinv/list_{}.html'.format(i) for i in range(48)]
        bizhi_360_one = random.choice(bizhi_360)
        wang_zhan = [bizhi_360_one]
        self.a = random.choice(wang_zhan)
    def huoqu(self):

          # 模擬訪問者
        ua = UserAgent().random
        headers 
 
= {"User-Agent": ua}
        data = requests.get(url=self.a, headers=headers)
        data.encoding= "utf-8"
        data= data.text
        s = etree.HTML(data)
        meinv_liebiao = s.xpath('//*[@id="main"]/div/div[1]/ul/li/a//@href')
        if len(meinv_liebiao) >1 :
            meinv = random.choice(meinv_liebiao)
            s = 'http://bizhi360.com'
            url = s + meinv
            self.xiazai(url)
        else:
            pass
    def xiazai(self,url):
        ua = UserAgent().random
        headers = {"User-Agent": ua}
        data = requests.get(url=url, headers=headers)
        data.encoding = "utf-8"
        data =data.text
        s = etree.HTML(data)
        meinv_tupian = s.xpath('//*[@id="main"]/div/div[1]/div[2]/ul/li/a//@href')
        if len(meinv_tupian) >1 :
            meinv = random.choice(meinv_tupian)
            s = 'http://bizhi360.com'
            url1 = s + meinv
            print(url1)
            self.xiazai_tupian(url1)
        else:
            meinv_url = s.xpath('//*[@id="main"]/div/div[1]/div[2]/figure/a//@href')
            try:
                url = meinv_url[0]
                response = requests.get(url,headers=headers)
                # 獲取的文字實際上是圖片的二進位制文字
                img = response.content
                # 將他拷貝到本地檔案 w 寫  b 二進位制  wb代表寫入二進位制文字
                # 儲存路徑
                path1 = os.getcwd()
                path = path1 + '\\1.jpg'
                with open(path, 'wb') as f:
                    f.write(img)
            except Exception as ex:
                print("出錯")

    def xiazai_tupian(self,url1):
        ua = UserAgent().random
        headers = {"User-Agent": ua}
        data = requests.get(url=url1, headers=headers)
        data.encoding = "utf-8"
        data = data.text
        s = etree.HTML(data)
        meinv_tupian = s.xpath('//*[@id="main"]/div[1]/div[1]/div[2]/figure/a//@href')
        try:
            url = meinv_tupian[0]
            response = requests.get(url,headers=headers)
            # 獲取的文字實際上是圖片的二進位制文字
            img = response.content
            # 將他拷貝到本地檔案 w 寫  b 二進位制  wb代表寫入二進位制文字
            # 儲存路徑
            path1 = os.getcwd()
            path = path1+ '\\1.jpg'
            with open(path, 'wb') as f:
                f.write(img)
        except Exception as ex:
            print("--------出錯繼續----")


class k4_bizhi():
    def __init__(self):
        num = random.randint(1,171)
        bizhi_360 = ('http://pic.netbian.com/4kmeinv/index_{}.html'.format(num))
        self.a = bizhi_360
    def huoqu(self):
        ua = UserAgent().random
        headers = {"User-Agent": ua}
        data = requests.get(url=self.a, headers=headers)
        data.encoding = "utf-8"
        data = data.text
        s = etree.HTML(data)
        meinv_liebiao = s.xpath('//*[@id="main"]/div[3]/ul/li/a//@href')
        if len(meinv_liebiao) >1 :
            meinv = random.choice(meinv_liebiao)
            s = 'http://pic.netbian.com'
            url = s + meinv
            self.xiazai(url)
        else:
            pass
    def xiazai(self,url):
        ua = UserAgent().random
        headers = {"User-Agent": ua}
        data = requests.get(url=url, headers=headers)
        data.encoding = "utf-8"
        data = data.text
        s = etree.HTML(data)
        meinv_tupian = s.xpath('//*[@id="img"]/img//@src')
        try:
            s = 'http://pic.netbian.com'
            url1 = s + meinv_tupian[0]
            response = requests.get(url1, headers=headers)
            # 獲取的文字實際上是圖片的二進位制文字
            img = response.content
            # 將他拷貝到本地檔案 w 寫  b 二進位制  wb代表寫入二進位制文字
            # 儲存路徑
            path1 = os.getcwd()
            path = path1 + '\\1.jpg'
            with open(path, 'wb') as f:
                f.write(img)
        except Exception as ex:
            print("--------出錯繼續----")

class k4_weimei():
    def __init__(self):
        num = random.randint(1, 6)
        bizhi_360 = ('http://www.4kbizhi.com/meinv/index_{}.html'.format(num))
        self.a = bizhi_360
    def huoqu(self):

          # 模擬訪問者
        ua = UserAgent().random
        headers = {"User-Agent": ua}
        data = requests.get(url=self.a, headers=headers)
        data.encoding= "utf-8"
        data= data.text
        s = etree.HTML(data)
        meinv_liebiao = s.xpath('/html/body/div[2]/div[1]/ul/li/a//@href')
        meinv_liebiao1 = s.xpath('/html/body/div[2]/div[2]/ul/li/a//href')
        meinv_lie = meinv_liebiao +meinv_liebiao1
        if len(meinv_lie) >1 :
            meinv = random.choice(meinv_liebiao)
            meinv= meinv.replace('.html', '')
            s = 'http://www.4kbizhi.com'
            url = s + meinv + '-1920x1080' +'.html'
            self.xiazai(url)
        else:
            pass
    def xiazai(self,url):
        ua = UserAgent().random
        headers = {"User-Agent": ua}
        data = requests.get(url=url, headers=headers)
        data.encoding = "utf-8"
        data =data.text
        s = etree.HTML(data)
        meinv_tupian = s.xpath('/html/body/div[2]/img//@src')[0]
        b = meinv_tupian.replace('small', '')
        c = b.split('/')
        c.pop()
        c = '/'.join(c)
        b = b.split('/')[-1]
        b = b[:11]
        meinv_tupian_url = c + '/' + b + '.jpg'
        try:
            s = 'http://www.4kbizhi.com'
            url1 = s + meinv_tupian_url
            response = requests.get(url1,headers=headers)
            # 獲取的文字實際上是圖片的二進位制文字
            img = response.content
            # 將他拷貝到本地檔案 w 寫  b 二進位制  wb代表寫入二進位制文字
            # 儲存路徑
            path1 = os.getcwd()
            path = path1 + '\\1.jpg'
            with open(path, 'wb') as f:
                f.write(img)
        except Exception as ex:
            print("出錯")
class tupian_zhijia():
    def __init__(self):
        num = random.randint(1, 11)
        bizhi_360 = ('https://www.tupianzj.com/bizhi/DNmeinv/list_77_{}.html'.format(num))
        self.a = bizhi_360
    def huoqu(self):

          # 模擬訪問者
        ua = UserAgent().random
        headers = {"User-Agent": ua}
        data = requests.get(url=self.a, headers=headers)
        data.encoding= "utf-8"
        data= data.text
        s = etree.HTML(data)
        meinv_liebiao = s.xpath('//*[@id="container"]/div/div/div[3]/div/ul/li/a//@href')

        if len(meinv_liebiao) >1 :
            meinv = random.choice(meinv_liebiao)
            meinv= meinv.replace('.html', '')
            s = 'https://www.tupianzj.com'
            url = s + meinv + '_1920x1080' +'.html'
            self.xiazai(url)
        else:
            pass
    def xiazai(self,url):
        ua = UserAgent().random
        headers = {"User-Agent": ua}
        data = requests.get(url=url, headers=headers)
        data.encoding = "utf-8"
        data = data.text
        meinv_tupian = re.findall(r"if\(imgSize==\"1920x1080\"\) picurl='.*",data)
        meinv_tupian = ''.join(meinv_tupian)
        meinv_tupian = meinv_tupian.replace('\'', '')
        meinv_tupian = meinv_tupian.replace(';', '')
        meinv_tupian =  meinv_tupian.split('=')[-1]
        meinv_tupian1 = ''.join(meinv_tupian)
        self.xiazai_tupian(meinv_tupian1)
    def xiazai_tupian(self,url1):
        try:
            ua = UserAgent().random
            url = str(url1)
            headers = {"User-Agent": ua}
            request = urllib.request.Request(url, headers=headers)
            response = urllib.request.urlopen(request)
            # 獲取的文字實際上是圖片的二進位制文字
            img = response.read()
            # response = requests.get(url, headers=headers)
            # img = response.content
            # 將他拷貝到本地檔案 w 寫  b 二進位制  wb代表寫入二進位制文字
            # 儲存路徑
            path1 = os.getcwd()
            path = path1 + '\\1.jpg'
            with open(path, 'wb') as f:
                f.write(img)
        except Exception as ex:
            print("出錯")


if __name__== '__main__':
    liebiao = [1,2,3,4]
    a= random.choice(liebiao)
    if a ==1:
        bizhi_360().huoqu()
    elif a==2:
        k4_bizhi().huoqu()
    elif a ==3:
        k4_weimei().huoqu()
    elif a==4:
        tupian_zhijia().huoqu()
    path1 = os.getcwd()
    path = path1 +"\\1.jpg"  # 圖片路徑
    try:
        set_wallpaper(path)
    except:
        print('圖片為下載！')

來看效果圖：

自己可以打包成exe檔案，用win10自帶的任務工具，設定成多久啟動一次。也可以寫成bat檔案，在寫成vbs啟動bat檔案去除程式碼框，放在桌面雙擊就換一站美女桌面桌布。