下面的程式碼實現每個月執行：其中呼叫了一個判斷是否為最後一天的方法

import datetime
import time
import pymysql
from isLastDayOfMonth import isLastDayMonth

def doSth1():

    # 連結資料庫
    conn = pymysql.Connect(
        host='192.0.9.169',
        port=5507,
        user='writer',
        passwd='Apsdf',
        db='api_data',
        charset='utf8'
    )
    cur = conn.cursor()
    cur.execute('''select * from table2''')
    conn.commit()
    cur.close()
    conn.close()
    # 假裝做這件事情需要一分鐘
    time.sleep(60)

def main(h=23 , m=0):
    while isLastDayMonth(datetime.datetime.now()) ==1:
        while True:
            now = datetime.datetime.now()

            # 到達設定時間，結束內迴圈

            if now.hour == h and now.minute == m:
                break

            # 不到時間就等20秒之後再次檢測

            time.sleep(20)

            # 做正事，一天做一次

        doSth1()

if __name__ == '__main__':
    main()

判斷是否最後一天：

import time,datetime
# 當前時間
now_time = datetime.datetime.now()
now_time_mk = time.mktime(now_time.timetuple())  # 當前時間戳
# 下月第一天最後一秒時間
month = now_time.month
if month == 12:
    month = 0
def isLastDayMonth(i):
    first_day = datetime.datetime(now_time.year, now_time.month + 1, 1, 23, 0, 0)
    # print(first_day)
    # 上個月最後一天
    up_last = first_day - datetime.timedelta(days=1)
    # print(up_last)
    # 上個月第一天第一秒
    up_first_day = datetime.datetime(up_last.year, up_last.month, 1)
    # print(up_first_day)
    if i == up_last:
        return 1

    else:
        return 0

def main():
    isLastDayMonth(datetime.datetime.now())

if __name__ == '__main__':
    main()