正確的右對齊方法：

panel = wx.Panel(self)
button = wx.Button(panel, label = _(u'確定'), size = (60, 28))

hbox = wx.BoxSizer(wx.HORIZONTAL)
hbox.Add(button, 0, wx.ALL | wx.ALIGN_RIGHT, 10)
panel.SetSizer(hbox)
panel.SetAutoLayout(True)

Add(self,item, proportion=0,flag=0, border=0, userData=None)

item,與userData引數就不必講解了，主要是proportion，flag，border三者的配合.

當flag有wx.EXPAND值時， proportion取0表示橫向擴充套件，大於零表示同時橫豎擴充套件，小於零應該只擴充套件豎方向。

當然flag中 存在wx.TOP，wx.BOTTOM，wx.LEFT，wx.RIGHT，wx.ALL中值時，表示與其它控制元件保持多少畫素的距離，border引數指定

最後flag中的wx.ALIGN_* 開頭的值就表示對齊方向，

例如如果想某控制元件一直右對齊，就在此控制元件左邊放一個空sizer，如: box.Add((1,1), 0, wx.EXPAND,0 ), 其中必需有expand,第二個引數取0

下面是沒找到官方正確佈局的異端方法，大家學。

wx 佈局真蛋痛，還是我沒找到方法使控制元件右對齊. 最後只能自繪，繫結EVT_SZIE事件

#coding:utf-8

import wx

class ButtonBarPanel(wx.Panel):
    def __init__(self, parent, pos):
        super(ButtonBarPanel, self).__init__(parent = parent, id = -1, pos = pos, size = (510, 32), style = wx.NO_BORDER)
        tsize = (24,24)
        bmpBack =  wx.ArtProvider.GetBitmap(wx.ART_NEW, wx.ART_TOOLBAR, tsize)
        bmpForward = wx.ArtProvider.GetBitmap(wx.ART_FILE_OPEN, wx.ART_TOOLBAR, tsize)
        
        self._btBack = wx.BitmapButton(self, 10, bmpBack, (0, 0),
                       (bmpBack.GetWidth() + 8, bmpBack.GetHeight() + 8), wx.NO_BORDER)

        self._btBack.SetToolTipString("This is a bitmap button.")
        self.Bind(wx.EVT_BUTTON, self.OnClick, self._btBack)
        
        self._btGo = wx.BitmapButton(self, 20, bmpForward, (32, 0),
                       (bmpForward.GetWidth() + 8, bmpForward.GetHeight() + 8), wx.NO_BORDER)
        self._btGo.SetToolTipString("open file.")
        self.Bind(wx.EVT_BUTTON, self.OnClick, self._btGo)

        self._btNew = self.addBtn(30, u'新建資料夾', (64, 0))
        self._btOpen = self.addBtn(40, u'開啟', (152, 0))
        self._btShare = self.addBtn(50, u'共享', (240, 0))

        #TODO:....ADD btn

        self._ctrlSearch = wx.SearchCtrl(self, 80)
        self.Bind(wx.EVT_SIZE, self.OnReSize)

    def OnReSize(self, event):
        #在繫結的size事件中使search右對齊
        x, y = self.GetSize()
        w, h = self._ctrlSearch.GetSize()
        self._ctrlSearch.SetPosition((x - w - 8, 4))
        self.Refresh()

    def addBtn(self, id, lable, pos = (0, 0), tooltip = ''):
        bt = wx.Button(self, id, lable, pos, size = (88, 30), style = wx.NO_BORDER)
        if tooltip:
            bt.SetToolTipString(tooltip)
        else:
            bt.SetToolTipString(lable)
        self.Bind(wx.EVT_BUTTON, self.OnClick, bt)
        return bt
 
    def OnClick(self, event):
        print "tool %s clicked\n" % event.GetId()
     
class F(wx.Frame):
    def __init__(self, parent, id, title):
        wx.Frame.__init__(self, parent, id, title, size = (500, 250))

        menubar = wx.MenuBar()
        file = wx.Menu()
        file.Append(1, '& Quit', 'Exit Calculator')
        menubar.Append(file, ' & File')
        self.SetMenuBar(menubar)
        ButtonBarPanel(self, (20, 20))
        self.Bind(wx.EVT_MENU, self.OnClose, id = 1)
        self.Show(True)
        
    def OnClose(self, event):
        self.Close()

app = wx.App()
F(None, -1, 'F')
app.MainLoop()