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生物資訊專有名詞積累

orthologue gene : 同源基因

原文:

1-to-1 orthologues Orthologues A type of orthologue assigned for a pair of species where only one copy is found in each species.
1-to-many orthologues Orthologues A type of orthologue assigned for a pair of species where one gene in one species is orthologous to multiple genes in the other species, due to (a) duplication event(s) in the second species.

同源基因分為兩種,一種是1-to-1 orthologues,另一種是1-to-many orthologues。1-to-1 orthologues是指,在一些存在同源基因的物種中,該同源基因在這些物種只存在1個拷貝;而1-to-many orthologues是在一個物種中的基因與另一個物種的多個基因相似,這種現象是由基因的複製引起的

Linkage disequilibrium: 連鎖不平衡

Haplotype (variation) Linkage disequilibrium A set of variant alleles in a contiguous genomic region. A haplotype block describes a set of alleles which tend to be inherited together.

連鎖不平衡指的是對於基因組上的一段連續的區域而言,這些區域上的位點總是傾向於一起遺傳,這意味著,這些區域上的變異也總是傾向於一起遺傳。

Primary assembly Genome assembly The underlying genome sequence, without alternative sequence included.

詞彙參考來源:

metagenomics: 巨集基因組學